Trachea histology

Respiratory System Histology Gartner & Hiatt Atlas (5th ed): Plates 12-2, -4, -5, pp. 256-263 Text (Junqueira's 12th ed): Ch 17, Respiratory System, pp. 298-315 I. Trachea Slide 40 (trachea, H&E) Slide 126 (trachea & esophagus, cross sect, H&E) Slide 127 (trachea, cross sect., trichrome) The epithelium lining the trachea is typical respiratory epithelium (ciliated pseudostratified columnar) basement membrane, which you can see as a narrow pink-staining region immediately basal to the epithelium. This epithelium plus its underlying layer of loose connective tissue (the lamina propria) make up the tracheal mucosa. The layer under the mucosa is the submucosa wherein you’ll find numerous seromucous glands slide #40 happens to show these fibers quite well (cut in cross section, so they appear as eosinophilic, glass-like dots) Outside the connective tissue layers, observe the C-shaped rings of hyaline cartilage slide #127 that are stained with Masson’s trichrome adventitia. II. Intrapulmonary Conducting Passageways Slide 129_20x (lung, H&E) Slide 130_20x (lung, H&E) Slide 130-1_40x (lung, H&E) Slide 130-2_40x (lung, H&E) Slide 132_20x (lung, H&E) Slide 132_40x (lung, H&E) A. Bronchi: The trachea bifurcates into two primary bronchi, which enter the lung and then branch several times to give rise to smaller secondary and tertiary bronchi plates rather than rings of cartilage, and in having a layer of smooth muscle between the lamina propria and submucosa. In smaller branches, the ...

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Trachea is a fibro cartilaginous tube that allow expansion in width and extension during inspiration. In trachea histology, you will find the same histological features of general tubular organs with some special characteristics features. After finishing this article you will able to identify the trachea histology slide under light microscope easily at laboratory. Table of Contents • • • • • • • • • Trachea histology You know trachea is called the windpipe and largest in diameter and length of respiratory tubes That provides the passageways between larynx and bronchi. In trachea histology you will find the four different coats, similar to the You will find the following four different layers in trachea histology slide – #1. Tunica mucosa layer of trachea #2. Tunica submucosa layer of trachea #3. Muscularis mucosa layer of trachea structure and #4. Adventitia of trachea structure I will discuss details on these four different layers of trachea structure; but now I would like to enlist the important structure that you might identify from the trachea slide under light microscope. #2. Lamina propria of trachea structure #3. Tracheal gland #4. Hyaline cartilage of trachea #5. Trachealis muscles #6. Adventitia layer of trachea structure Trachea histology slide identification Do you want to identify the trachea histology slide under light microscope? Well, I will show you the real trachea slide picture with the identification points. #2. The mucosa of the smaple tissue is folded ...

The trachea is a tubular organ that directs air from the larynx further into the bronchi , while improving its properties. The cross-section shows its basic structure: the horseshoe-shaped hyaline cartilage discs, both ends of which are connected by a straight paries membranaceus made of smooth muscle and elastic fibers. Tunica mucosa [ | ] Lamina epithelialis [ | ] The trachea is mostly lined by a multilayered cylindrical epithelium with cilia and goblet cells , the number of which increases aborally. Mucus formed by goblet cells and displaced by lashes together forms an important cleansing mechanism . The exception is carina tracheae , which is protected by a more resistant layered squamous epithelium . At the point where the trachea is divided into bronchi, the air flows turbulently , which puts more strain on the mucosa. Lamina propria mucosae [ | ] A layer of very cellular sparse collagenous connective tissue , it contains blood vessels , unmyelinated nerves and seromucinous glands . There are also more or less numerous plasma cells and lymphocytes , which can even form follicles ( BALT ). Tunica submucosa [ | ] Unlike other organs, the submucosa consists of a sparse ligament similar to the lamina propria . Due to this, and due to the absence of muscles of the lamina muscularis mucosae, it is difficult to find the boundary between the lamina propria and the submucosa. Numerous lymphatic infiltration from the lamina propria intervenes here, and larger blood and lymphat...

\( \newcommand\) • • • • • The trachea, or windpipe, is a tube that connects the pharynx or larynx to the lungs, allowing the passage of air. Key Points • The trachea is lined with pseudostratified ciliated columnar epithelium cells with goblet cells that produce mucus. • There are about 15 to 20 C-shaped cartilaginous rings that reinforce the anterior and lateral sides of the trachea to protect and maintain the airway, leaving a membranous wall (pars membranacea) dorsally without cartilage where the C-shape is open. • The cartilaginous rings are C-shaped to allow the trachea to collapse slightly at the opening so that food can pass down the esophagus. • The trachealis muscle connects the ends of the open part of the C-shaped rings and contracts during coughing, reducing the size of the lumen of the trachea to increase the air flow rate. • The esophagus lies posteriorly to the trachea. • The mucocilliary escalator helps prevent pathogens from entering the lungs. • The trachea is part of the conducting zone and contributes to anatomical dead space. Key Terms • cilia: Tiny, hair-like projections from a cell. • mucocilliary escalator: The ladder formed by mucus and cilia in the trachea that pushes mucus up the trachea and into the pharynx to prevent mucus pathogens from entering the lungs. • anatomical dead space: The space in the respiratory tract that isn’t involved in alveolar ventilation and is part of the normal conducting zone of the respiratory system. The trachea: Thi...

Overview: The goal of this lab is to examine the organization of the conducting and respiratory portions of the respiratory system. In your slides you should be able to find excellent examples of epithelial transitions along the tract. Attention should be paid to the key structural features summarized in the table below: Other Trachea Pseudost.Columnar Ciliated Goblet C-shaped At opening of C-shaped cartilage Serous/Mucous ~2 cm -- Bronchi Pseudost. Columnar Ciliated Goblet Pieces Yes (encircles lumen) Serous/Mucous ~1.5 - 0.05 cm Enters lung Bronchioles to Terminal Bronchioles Simple Columnar Ciliated Club cells No Yes No 0.5 - 0.2 mm No Alveoli in Walls Respiratory Bronchioles Simple Cuboidal (some cilia) Club cells No Yes No ~0.15 mm Alveoli in Walls Alveolar Duct Mostly Simple Squamous No No Yes/No No ~0.1 mm -- Alveoli Simple Squamous (Type I and II cells) Type II Cell No No No <0.5 mm -- I. Slide Descriptions Webslide UVa_077: Larynx and trachea, coronal section, H&E The larynx is a passageway for air between the oropharynx and trachea which also functions in the production of sound. The epithelial lining varies by location: the vestibular folds (or "false" vocal folds) are lined by a mixture of stratified squamous to stratified columnar epithelium whereas the true vocal folds are typically covered by stratified squamous non-keratinized epithelium that sometimes can keratinize in response to repeated injury. Inferior to the vocal folds, the epithelium goes back to st...